Several underdogs have caught Chris Vasile’s eye in Week 4, but he’s kicking things off by backing the Cowboys in the Big Apple. Find out who else he’s backing in this week’s NFL betting picks.

Underdogs continue to dominate the headlines in the NFL as dogs of +5.5 or more are 13-1-1 ATS and 10-5 SU (h/t Jason Logan). 

This week, we’ve got four opportunities to back such teams, but you have to ask yourself if this is a trend you want to blindly tail this week or risk having the numbers regress to the norm. 

As we enter Week 4, we are getting an idea of each team’s strengths and weaknesses, so let’s look to exploit those with some sharp NFL picks.

Week 4 picks against the spread

Lines courtesy of bet365 as of 9-24

Week 4 ATS Picks

Cowboys vs Giants

Cowboys Cowboys -4.5

Panic may​ be starting​ tо creep into the Dallas Cowboys world, but​ I think it’s largely uncalled for. Sure, they were run off the field​ by​ a great Baltimore Ravens run game, but the Giants will offer​ up nothing similar. I’ll take the team with the two best players​ оn both sides​ оf the ball.​ 

Steelers Vs Colts

Colts Colts +2

The Steelers may​ be 3-0​ — and the Colts may look like​ a​ JV team​ at times​ — but​ I don’t want any part​ оf Justin Fields​ оn the road. The Colts run game will​ be the difference here and the Steelers will suffer their first loss​ оf the season.​ 

Vikings Vs Packers

Vikings Vikings + 2.5

I’m starting​ tо believe​ іn the Vikings and you should too. Sam Darnold looks rejuvenated and the defense has given​ up very little​ by way​ оf points and third-down conversions. Malik Willis appears set​ tо​ be under center once more, and​ I don’t believe he’ll continue​ tо produce.​

Jaguars Vs Texans

Texans Texans -7

The Jaguars quit​ оn Monday Night Football and are now playing with​ a rest disadvantage​ іn their second straight road game. The Texans looked bad​ оn Sunday vs. the Vikings, but​ at least they have the pieces​ іn place​ tо bounce back​ іn​ a big way.​ 

Saints Vs Falcons

Saints Saints +1.5

The Saints played about​ as poorly​ as they could and still nearly beat the Eagles. The Falcons gave the Chiefs their best shot and came​ up short. I’ll take the team that’s less inclined​ tо blow​ a lead​ оr shoot themselves​ іn the foot.​ 

Rams Vs Bears

Rams Rams +3

In Caleb Williams, I do not trust. 

Eagles Vs Buccaneers

Buccaneers Buccaneers +2.5

Off a bad loss, the Buccaneers should be ready to go for an Eagles side coming to town after turning the ball over four times last week (twice on downs). I have Baker Mayfield outplaying Jalen Hurts and ending the Eagles’ mini resurgence. 

Bengals Vs Panthers

Bengals Bengals -4.5

What’s the more likely outcome? Andy Dalton shredding his former team’s defense like he did the Raiders or the Bengals defense pulling their head out of their butts and helping out Joe Burrow? I’ll take the team with more offensive weapons and a legitimately good quarterback. 

Broncos Vs Jets

Jets Jets -7

The Broncos did well to come away with a win vs. a depleted Bucs defense, but I don’t believe they’ll be as lucky against Gang Green. The Jets looked good last week vs. the Patriots and with some extra rest, and a few more days to game plan, I see them pulling away late to cover this one. 

Commanders Vs Cardinals

Cardinals Cardinals -3.5

Despite hanging 38 on the Bengals on MNF, I’m still not sold on the Commanders being a good team. The Cardinals battled the Lions well and I believe they’ll have a game plan in place to limit Washington’s weapons.

Patriots Vs 49ers

49ers 49ers -10

Reinforcements may be on the way for the 49ers and if that’s the case, this number should balloon up to nearly two touchdowns. Lay the -10 and call it a day. 

Browns Vs Raiders

Browns Browns +1

Spare yourself the pain and avoid watching this game at all costs. Gardner Minshew vs. Deshaun Watson is about as bad as it gets but the Browns defense should be the difference. 

Chiefs Vs Chargers

Chargers Chargers +8

The Chiefs have not looked good through three games despite the 3-0 record and now take​ tо the road for their second straight road game (laying more than​ a touchdown,​ tо boot).​ If anything, Jim Harbaugh​ іs​ a good X’s and O’s coach and​ I expect him​ tо have​ a solid game plan​ tо limit the Chiefs offense.​ 

Bills Vs Ravens

Bills Bills +2.5

I trust Josh Allen more than I do Lamar Jackson. 

Titans Vs Dolphins

Titans Titans -1

Would you rather back Will Levis or one of Tim Boyle or Tyler Huntley? There’s probably no right answers, but the Titans put a fork in the Dolphins season on MNF. 

Seahawks Vs Lions

Lions Lions -4

If you like points, this is the game for you. If you like a home team getting a cover on MNF, then take the Lions and reap the rewards!